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January 5, 2024

After four years of wonderful experience at the University of Kansas, Our research group is now relocated to the University of Chicago. We are happy to join the Genetic Medicine Section, Department of Medicine, Biological Sciences Division at UC!  

June 30, 2023

Our project entitled Treatment of Parkinson’s Disease using alpha-synuclein RNA degraders was selected for Bill and Amy Gurley Impact Award by Parkinson's Foundation. Thank you Parkinson's Foundation! 

June 16, 2023

Shalakha Hegde passed Med Chem Comprehensive Oral Exam and is now a Ph.D. Candidate! Congratulations, Shalakha!

March 30, 2023

Our project entitled Development of an Oral STING Agonist for Cancer Treatment was selected for funding by KU Research GO. Thank you, KUOR! (

January 7, 2023

Mercy Haboro was admitted to our graduate program and transitioned from postbacc to a first-year graduate student in the lab. Congratulations, Mercy!


December 20, 2022

Jolie (Lixian) Zhou joined the lab as a first-year graduate student! Welcome, Jolie! 

November 4, 2022

KU Cancer Center Pilot Project Award will fund our collaborative work with Dr. Gregory Gan at KUMC on STING agonists for one year. Thank you KUCC! 

September 2, 2022

Congratulations to Junxing! His manuscript entitled "Cellular Target Deconvolution of Small Molecules using a Selection-based Genetic Screening Platform" was accepted for publication in ACS Central Science. 

August 24, 2022

Congratulations to Shalakha! She was awarded Dr. Gregory and Frances L. Lauver Medicinal Chemistry Fellowship in FY23.

August 1, 2022

Our RNA-targeting chimera work is now funded by NIH/NIGMS R35 MIRA award. Thank you, NIH! 

June 24, 2022

Our collaborative work with Dr. Yang I. Li at the University of Chicago will be supported by the W. M. Keck Foundation for the next three years. Thank you, W. M. Keck Foundation! 

June 1, 2022

KU Frontiers IAMI Trailblazers Pilot Award will fund our work on splicing modulators for one year. Thank you, KU Frontiers! 


March 2, 2022

Congratulations to Zhichao, Shalakha, and Junxing! Their manuscript entitled "CRISPR-mediated Enzyme Fragment Complementation Assay for Quantification of the Stability of Splice Isoforms" was accepted by ChemBioChem. 

July 26, 2021

Congratulations to Ankita for her successful MS thesis defense! 

June 26, 2021

Congratulations to Zhichao! His first-authored paper "Recognition of single-stranded nucleic acids by small-molecule splicing modulators" was accepted by Nucleic Acid Research. 

December 21, 2020

Congratulations to Junxing! His first-authored paper "The RNA Architecture of the SARS-CoV-2 3′-Untranslated Region" was published in Viruses! Click here for reading. 

July 21, 2020

Jingxin is awarded by BioNexus KC for the treatment of spinal muscular atrophy! Click here for the press release.

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